Polynucleotides - what are they ?

With 41 years of scientific research and development, 36 years of medical application, 1.8 million uses and no adverse or allergic reactions, Polynucleotides are the gold standard in true skin regeneration. Utilising filtered, ultra purified and sterilised natural DNA fractions, this injectable serum offers some serious benefits and incredible, visible results.

what are polynucelotides?

In the world of aesthetics, polynucleotides are known as the future of regenerative injectables – hailed for their ability to rejuvenate and regenerate the skin, similarly to skin boosters like Seventy Hyal 2000. However, unlike skin boosters, injectable polynucleotides are renowned for their wound-healing and bio-stimulating properties. Although similar to skin boosters, polynucleotide injectables are separated and well-recognised for their complex structures and ability to rejuvenate the skin with a natural result.

Biostimulators means they kick-start regeneration in the skin.’ Isn’t that what all the HA-based skinboosters do such as Profhilo & Seventy Hyal? Yes, but rather than just providing hydration, polynucleotides are more like food or medicine for the cells, to make them produce collagen and elastin in a more meaningful way, and they also improve the extra cellular matrix [the layer of the skin in which the fibroblasts live] and they’re anti-inflammatory, too.’

what are polynucelotides made from?

They’re biopolymers – stretchy molecules made from fragments of fish DNA extracted from salmon or trout which closely resemble human DNA.

what if I’m allergic to fish?

Then these are not for you. Stick with hyaluronic-acid-based injectable moisturisers.

how do polynucleotides work in the skin?

They target the fibroblasts and promote hydration of the skin, and collagen synthesis and they also increase the number of fibroblasts. At the same time, they scavenge up free radicals [unstable molecules which accelerate ageing processes in the skin] and help build up the extra-cellular matrix.

what are polynucleotides good for?

All that collagen-boosting, extra hydration and elasticity means you can think of polynucleotides as a super-charged injectable moisture treatment. They can be a preventative treatment for younger skin, or a recovery treatment for ageing skin there are different varieties dependant on what is being treated

Polynucleotides are also used to counteract dark circles under the eyes and to strengthen the thin delicate skin around the mouth. The products are injected very superficially, and the procedures are incredibly quick and painless

Nucleofil is a popular brand of polynucleotide, and is great for use around the eyes, particularly for patients who aren’t suitable for tear trough filler, or who might have a tendency to go puffy if treated with a hyaluronic-acid based products.

what can you expect to see after polynucleotide injections?

In a nutshell, reduced wrinkling and crepiness and an improvement in skin tone and hydration. They can also be great for bringing down inflammation in the skin, which can reduce the redness of Rosacea for months at a time. They’re also useful for improving skin condition ahead of energy-based treatments like HIFU or Radio Frequency